‘Worrying’ new coronavirus variant detected in UK

An expert has warned that the E484K mutation is known to protect coronavirus variants from being neutralized by some vaccines. (AFP file photo)
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Updated 16 February 2021
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‘Worrying’ new coronavirus variant detected in UK

  • Scientists: Surge in new testing crucial to prevent spread

LONDON: A new coronavirus variant has been detected in the UK, with scientists warning that a surge in new testing is crucial to prevent its spread.

The B1525 variant contains an alarming set of new mutations, experts have said. It is the subject of a study by University of Edinburgh researchers, who warn that it has been found in 10 countries — including Denmark, the US and Australia — while there are 32 known cases in the UK.

The earliest forms of the variant, first detected in December, have been traced to the UK and Nigeria.

The University of Edinburgh team says B1525 shares many similarities with the B117 Kent variant but contains concerning new mutations, including the E484K spike protein that helps the virus enter cells.

The E484K mutation is also contained in the variants that emerged from South Africa and Brazil, and is believed to cause the virus to evade neutralizing antibodies.

Dr. Simon Clarke, an associate professor of cellular microbiology at the University of Reading, warned that the E484K mutation is known to protect coronavirus variants from being neutralized by some vaccines.

“We don’t yet know how well this new variant will spread, but if it’s successful it can be presumed that immunity from any vaccine or previous infection will be blunted,” he said.

“I think that until we know more about these variants, any variants that carry E484K should be subject to surge testing as it seems to confer resistance to immunity, however that’s generated.”

Ravi Gupta, professor of clinical microbiology at the University of Cambridge, also said surge testing is necessary, but warned that B1525 has other properties that “likely help it escape from our antibodies.”

Prof. Jonathan Stoye of the Francis Crick Institute said despite the spread of the new variant, surge testing poses several problems, including people at high risk of contracting coronavirus failing to come forward because they cannot afford the financial hit resulting from a positive test.

However, the similarities between coronavirus variants mean that modifications to existing vaccines could offer much-needed protection.

Stoye said: “This E484K change seems to be the key change at the moment to allow escape, so that’s the one you put into a tweaked vaccine.”


Mali, Burkina, Niger foreign ministers due in Moscow for talks

Updated 43 min 45 sec ago
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Mali, Burkina, Niger foreign ministers due in Moscow for talks

  • Sahelian countries are led by juntas who seized power in coups between 2020 and 2023 and have turned away from former colonial power France and moved closer to Russia
  • Russian mercenaries from the Wagner group and its successor Africa Corps are helping the Alliance of Sahel States (AES) battle extremists

ABIDJAN: The foreign ministers of Mali, Burkina Faso and Niger are due in Moscow this week for the first talks between their countries’ newly created confederation and Russia, they said in a statement.
The three Sahelian countries are led by juntas who seized power in coups between 2020 and 2023 and have since turned away from former colonial power France and moved closer to Russia.
They quit the Economic Community of West African States (ECOWAS) at the beginning of the year, accusing the regional bloc of being subservient to France, and have formed the Alliance of Sahel States (AES), originally set up as a defense pact in 2023 but which now seeks closer integration.
The three foreign ministers will be in the Russian capital on Thursday and Friday at the invitation of their counterpart Sergei Lavrov to “take part in the first session of AES-Russia consultations,” the ministers said in a statement posted on Facebook by the Malian foreign ministry, which holds the presidency of the confederation.
“This meeting is part of the shared desire of the heads of state of the AES confederation and the Russian Federation to extend their partnership and their political dialogue at the confederal level and to place them at the heart of their diplomatic, development and defense agenda,” they said.
Russian mercenaries from the Wagner group and its successor Africa Corps are helping the AES countries battle extremists, whose attacks have killed tens of thousands of people in the three countries.
Moscow has also concluded defense agreements with Mali, Burkina and Niger and has supplied military equipment.
It also cooperates with the AES on energy and mining.


King Charles back to work after ‘minor bump’ in cancer treatment

Updated 01 April 2025
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King Charles back to work after ‘minor bump’ in cancer treatment

  • Officials regarded the short hospital stay of a few hours as a “minor bump” in his medical journey
  • Other engagements later in the week will include the king’s weekly meeting with Prime Minister Keir Starmer

LONDON: King Charles III on Tuesday carried out his first public engagement since a short spell in hospital last week for side effects from his cancer treatment.
Charles, 76, on Thursday postponed all his appointments for the rest of the day and for Friday on doctors’ advice after suffering some temporary symptoms, Buckingham Palace said.
Officials regarded the short hospital stay of a few hours as a “minor bump” in his medical journey.
In the first of his engagements for this week, Charles was all smiles as he handed out honors at Windsor Castle west of London to leading figures including reigning world heptathlon champion Katarina Johnson-Thompson who was recognized with an Member of the Order of the British Empire (MBE) for her services to athletics.
Johnson-Thompson said afterwards the monarch “seemed in good spirits. You know it’s long, all day, because so many people are getting honored today.
“So he seems in really good spirits and I’m happy to see that he’s fit and well.”
Gardner and broadcaster Alan Titchmarsh, who received a Commander of the Order of the British Empire (CBE), also praised Charles’s “boundless energy.”
Other engagements later in the week will include the king’s weekly meeting with Prime Minister Keir Starmer.
A small number of appointments, however, had been rescheduled ahead of a state visit that Charles and his wife Queen Camilla will make to Italy next week.
Charles announced he had been diagnosed with an unspecified cancer in February last year.
He returned to work within two-and-a-half months and gradually ramped up his duties during the rest of 2024, including making several foreign trips which took him as far as Australia and Samoa.
Just six weeks after Charles’s cancer announcement came the news that his daughter-in-law Catherine, Princess of Wales, had also been diagnosed with cancer and had begun chemotherapy.
Catherine, who is married to heir to Charles’s eldest son Prince William, said in January that she was now in remission


Britain says anyone carrying out activity with Russian authorities now needs to register

Updated 01 April 2025
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Britain says anyone carrying out activity with Russian authorities now needs to register

  • Russian political parties that are controlled by the Russian government will also need to declare what they are doing
  • The program is a key tool for the “detection and disruption of harmful activity against our country”

LONDON: Britain’s government is placing Russia on the top tier of a government security program aimed at protecting the UK from malign foreign influence, the security minister said Tuesday.
Home Office minister Dan Jarvis told lawmakers that anyone or any company “carrying out activity as part of any arrangement” with Russian authorities — including government agencies, armed forces, intelligence services and the parliament — will need to register with the Foreign Influence Registration Scheme from July 1 or face five years in prison.
Russian political parties that are controlled by the Russian government will also need to declare what they are doing before they can carry out activity in the UK directly.
Britain’s government said the program is a key tool for the “detection and disruption of harmful activity against our country.”
Jarvis cited hostile Russian acts in recent years including the use of the deadly nerve agent Novichok to poison a Russian ex-spy and his daughter in 2018, the targeting of British members of Parliament through cyberattacks and other espionage tactics.
“And clearly Russia’s illegal invasion of Ukraine has highlighted its intent to undermine European and global security,” he added.
Iran was the first country to be listed under the program earlier this month. Lawmakers have questioned for months why China isn’t included.
“There is no question, in my mind, China should be in that enhanced tier,” said Chris Philp of the opposition Labour Party. “We know China engages in industrial-scale espionage, seeking to steal technology from government, universities and from industries. They repress Chinese citizens here and have sought to infiltrate our political system.”
Jarvis did not directly respond, only saying that his government is taking a “long-term and strategic approach” to managing its relationship with China.


Russia says told US about Ukrainian strikes on energy sites

Updated 01 April 2025
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Russia says told US about Ukrainian strikes on energy sites

  • Ukraine reported a Russian attack had left tens of thousands without power on Tuesday
  • Each side has accused the other of breaking a supposed deal to stop firing on energy sites

KYIV: Russia said Tuesday that it had complained to the United States about Ukrainian strikes on its energy sites, hours after Kyiv reported a Russian attack had left tens of thousands without power.
Each side has accused the other of breaking a supposed deal to stop firing on energy sites, though a formal agreement has not been put in place and what commitments each side has undertaken remain unclear.
Following separate meetings with US officials, the White House said both Ukraine and Russia had “agreed to develop measures for implementing” an “agreement to ban strikes against energy facilities of Russia and Ukraine.”
Russian President Vladimir Putin discussed allegations of Ukrainian “violations” in a private meeting of top security officials on Tuesday.
“We passed a list of violations... to the US National Security Adviser Mike Waltz,” Foreign Minister Sergei Lavrov said after the meeting.
“I have passed this list to the US Secretary of State Marco Rubio,” he added.
Russia’s defense ministry earlier accused Kyiv of striking Russian energy sites in the Russian region of Belgorod and the partially Moscow-controlled Ukrainian region of Zaporizhzhia.
The allegations come hours after Ukraine’s Foreign Minister Andriy Sybiga said tens of thousands were left without power in the southern Kherson region by a Russian strike.
Local authorities later said power supplies had been restored.
Russia has launched systematic aerial attacks on Ukrainian power plants and grid since invading in February 2022.
Putin last month rejected a joint US-Ukrainian proposal for an unconditional and full ceasefire.
Sybiga also said Kyiv and Washington were holding fresh talks on a minerals agreement that would give the United States access to Ukrainian natural resources in return for more support.
The two countries had planned to sign a deal in February on extracting Ukraine’s strategically important minerals, until a spectacular televised White House clash between US President Donald Trump and Ukrainian President Volodymyr Zelensky derailed the agreement.
Trump on Sunday warned Zelensky he would have “big problems” if Kyiv rejected the latest US proposal, details of which have not been published by either side.


Survivors still being found from Myanmar earthquake, but hopes begin to fade as deaths exceed 2,700

Updated 01 April 2025
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Survivors still being found from Myanmar earthquake, but hopes begin to fade as deaths exceed 2,700

  • “The needs are massive, and they are rising by the hour,” said Julia Rees, UNICEF’s deputy representative for Myanmar.
  • “The window for lifesaving response is closing”

BANGKOK: Rescue workers saved a 63-year-old woman from the rubble of a building in Myanmar’s capital on Tuesday, but hope was fading of finding many more survivors of the violent earthquake that killed more than 2,700 people, compounding a humanitarian crisis caused by a civil war.
The fire department in Naypyitaw said the woman was successfully pulled from the rubble 91 hours after being buried when the building collapsed in the 7.7 magnitude earthquake that hit midday Friday. Experts say the likelihood of finding survivors drops dramatically after 72 hours.
Death toll numbers forecast to increase
The head of Myanmar’s military government, Senior Gen. Min Aung Hlaing, told a forum for relief donations in Naypyitaw that 2,719 people have now been found dead, with 4,521 others injured and 441 missing, Myanmar’s state MRTV television reported.
He said that Friday’s earthquake was the second most powerful in the country’s recorded history after a magnitude 8 quake east of Mandalay in May 1912.
The casualty figures are widely expected to rise, but the earthquake hit a wide swath of the country, leaving many areas without power, telephone or cell connections and damaging roads and bridges, making the full extent of the devastation hard to assess.
Most of the reports so far have come from Mandalay, Myanmar’s second-largest city, which was near the epicenter of the earthquake, and Naypyitaw.
“The needs are massive, and they are rising by the hour,” said Julia Rees, UNICEF’s deputy representative for Myanmar.
“The window for lifesaving response is closing. Across the affected areas, families are facing acute shortages of clean water, food, and medical supplies.”
Myanmar’s fire department said that 403 people have been rescued in Mandalay and 259 bodies have been found so far. In one incident, 50 Buddhist monks who were taking a religious exam in a monastery were killed when the building collapsed, and 150 more are thought to be buried in the rubble.
Structural damage is extensive
The World Health Organization said that more than 10,000 buildings overall are known to have collapsed or been severely damaged by the quake..
The earthquake also rocked neighboring Thailand, causing a high-rise building under construction to collapse and burying many workers.
Two bodies were pulled from the rubble on Monday and another was recovered Tuesday, but dozens were still missing. Overall, there were 21 people killed and 34 injured in Bangkok, primarily at the construction site.
In Myanmar, search and rescue efforts across the affected area paused briefly at midday on Tuesday as people stood for a minute in silent tribute to the dead.
Relief efforts moving at a sluggish pace
Foreign aid workers have been arriving slowly to help in the rescue efforts, but progress lagged due to a lack of heavy machinery in many places.
In one site in Naypyitaw on Tuesday, workers formed a human chain, passing chunks of brick and concrete out hand-by-hand from the ruins of a collapsed building.
The state Global New Light of Myanmar newspaper reported Tuesday that a team of Chinese rescuers saved four people the day before from the ruins of the Sky Villa, a large apartment complex that collapsed during the quake. They included a 5-year-old and a pregnant woman who had been trapped for more than 60 hours.
It also reported two teenagers were able to crawl out of the rubble of the same building to where rescue crews were working, using their cellphone flashlights to help guide them. The rescue workers were then able to use details from what they told them to locate their grandmother and sibling.
International rescue teams from several countries are on the scene, including from Russia, China, India, the United Arab Emirates and several Southeast Asian countries. The US Embassy said an American team had been sent but hadn’t yet arrived.
Aid pledges pouring in as officials warn of disease outbreak risk
Meantime, multiple countries have pledged millions in assistance to help Myanmar and humanitarian aid organizations with the monumental task ahead.
Even before the earthquake, more than 3 million people had been displaced from their homes by Myanmar’s brutal civil war, and nearly 20 million were in need, according to the UN
Many were already lacking in basic medical care and standard vaccinations, and the destruction of water and sanitation infrastructure by the earthquake raises the risk of disease outbreaks, warned the UN’s Office for the Coordination of Humanitarian Affairs.
“The displacement of thousands into overcrowded shelters, coupled with the destruction of water and sanitation infrastructure, has significantly heightened the risk of communicable disease outbreaks,” OCHA said in its latest report.
“Vulnerability to respiratory infections, skin diseases, vector-borne illnesses such as dengue fever, and vaccine-preventable diseases like measles is escalating,” it added.
The onset of monsoon season also a worry
Shelter is also a major problem, especially with the monsoon season looming.
Since the earthquake, many people have been sleeping outside, either because homes were destroyed or out of fear of aftershocks.
Civil war complicates disaster relief
Myanmar’s military seized power in 2021 from the democratically elected government of Aung San Suu Kyi, sparking what has turned into significant armed resistance and a brutal civil war.
Government forces have lost control of much of Myanmar, and many places were dangerous or impossible for aid groups to reach even before the quake.
Military attacks and those from some anti-military groups have not stopped in the aftermath of the earthquake, though the shadow opposition National Unity Government has called a unilateral ceasefire for its forces.
The NUG, established by elected lawmakers who were ousted in 2021, called for the international community to ensure humanitarian aid is delivered directly to the earthquake victims, urging “vigilance against any attempts by the military junta to divert or obstruct humanitarian assistance.”
“Any obstruction to these efforts will have devastating consequences, not only due to the impact of the earthquake but also because of the junta’s continued brutality, which actively hinders the delivery of lifesaving assistance,” the group said in a statement.
The ceasefire plan for the armed wing of the NUG, called the People’s Defense Force, would have little effect on the battlefield, but could draw more international condemnation of continuing operations by the military, including air attacks reported by independent media.
A second armed opposition group, a coalition of three powerful ethnic minority guerrilla armies called the Three Brotherhood Alliance, announced Tuesday that it would also implement a monthlong unilateral ceasefire.
However, Min Aung Hlaing seemed to reject implementing a ceasefire, saying in his speech on Tuesday that the military will continue to take necessary defensive measures against some ethnic armed groups that were currently not carrying out combat operations, but were conducting military training, which amounted to hostile action.
It wasn’t immediately clear whether the military has been impeding humanitarian aid. In the past, it initially refused to allow in foreign rescue teams or many emergency supplies after Cyclone Nargis in 2008, which resulted in well more than 100,000 deaths. Even once it did allow foreign assistance, it was with severe restrictions.
In this case, however, Min Aung Hlaing pointedly said on the day of the earthquake that the country would accept outside help.
Tom Andrews, a monitor on rights in Myanmar commissioned by the UN-backed Human Rights Council, said on X that to facilitate aid, military attacks must stop.
“The focus in Myanmar must be on saving lives, not taking them,” he said.