WHO warns of falsified cough syrup ingredients seized in Pakistan

This photograph taken on December 2, 2021, shows a sign of the the World Health Organization (WHO) next to theirs headquarters, in Geneva. (AFP/File)
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Updated 16 April 2024
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WHO warns of falsified cough syrup ingredients seized in Pakistan

  • Five contaminated batches of propylene glycol falsely labelled as made by Dow Chemical units in Asia and Europe
  • Contaminated cough syrups linked to deaths of more than 300 children globally since late 2022

The World Health Organization issued an alert on Monday warning drugmakers of five contaminated batches of propylene glycol, an ingredient used in medicinal syrups, that appear to have been falsely labelled as manufactured by Dow Chemical units in Asia and Europe.

The Drug Regulatory Authority of Pakistan (DRAP) issued three alerts between January and March over high levels of ethylene glycol (EG), an industrial solvent known to be toxic, found in drums purportedly made by subsidiaries of Dow Chemical in Thailand, Germany and Singapore.

DRAP sent suspect drums of propylene glycol, a sweet-tasting alcohol used in over-the-counter medicines such as cough syrups, for testing. The samples were found to have EG contamination of 0.76-100 percent, according to the WHO. International manufacturing standards say only trace amounts of EG, below 0.1 percent, can be considered safe.

Contaminated cough syrups made in India and Indonesia have been linked to deaths of more than 300 children globally since late 2022. The medicines were found to contain high levels of EG and diethylene glycol, leading to acute kidney injury and death. In the Indonesia case, authorities found that one supplier had placed false Dow Thailand labels onto drums containing EG that it sold to a distributor for pharmaceutical use.

Several of the batches seized by DRAP were labelled as having been manufactured in 2023, the WHO said, months after the agency issued a global alert calling on drugmakers to verify the quality of their suppliers.

The WHO said Dow confirmed that the materials identified in its Monday alert and found by DRAP were not manufactured or supplied by the company.

“The propylene glycol materials identified in this alert are considered to have been deliberately and fraudulently mislabelled,” the WHO said, noting batches may have been distributed to other countries and still be in storage.

Dow did not immediately respond to a request for comment.

The WHO alert comes the same week regulators in Tanzania and Rwanda joined Nigeria, Kenya and South Africa to recall batches of Johnson & Johnson children’s cough syrup after Nigeria said it found high levels of diethylene glycol, an industrial solvent known to be toxic.

The batch of Benylin Paediatric syrup recalled was made by J&J in South Africa in May 2021, although Kenvue now owns the brand after a spin-off from J&J last year.


Ten highest winning run-chases in Test history

Updated 9 sec ago
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Ten highest winning run-chases in Test history

  • England’s 371-run chase at Headingley joins elite list of historic Test wins
  • Record fourth-innings pursuits span from Bradman’s brilliance to debutant heroics

LEEDS, United Kingdom: England completed the tenth highest fourth-innings run chase in Test history with a pursuit of 371 that sealed a five-wicket over India at Headingley on Tuesday.
Below AFP Sport looks at the largest targets chased down in 148 years of Test cricket:

After both teams made 240 in their first innings, Australia made 417 in their second innings and would have expected an attack featuring fast bowlers Glenn McGrath, Jason Gillespie and Brett Lee to finish the job. But hundreds from Ramnaresh Sarwan and Shivnarine Chanderpaul changed the game before an unbroken partnership of 46 between Omari Banks and Vasbert Drakes sealed a three-wicket win.

Australia appeared to have put the game beyond South Africa’s reach but Proteas captain Graeme Smith’s hundred and a century from AB de Villiers helped guide the visitors to a dominant six-wicket success.

Still one of the most famous Tests of them all, England captain Norman Yardley did not declare his side’s second innings until the fifth morning. But Australia still scored 400 runs in under a day’s play, with opener Arthur Morris making 182 and Don Bradman, widely regarded as cricket’s greatest batsman, an unbeaten 173 that sealed a seven-wicket triumph.

Alvin Kallicharran’s hundred built an imposing West Indian lead, but centuries from Sunil Gavaskar and Gundappa Viswanath took India to an eventual total of 406-4. The match proved a turning point as his spinners’ failure persuaded West Indies captain Clive Lloyd to break with convention by building an attack around four fast bowlers — a policy that helped his side dominate Test cricket for the next 15 years.

West Indies batsman Kyle Mayers enjoyed an astounding start to his Test career with an extraordinary 210 not out, putting on 216 with fellow debutant Nkrumah Bonner (86) to see the visitors to a three-wicket win.

Asela Gunaratne made a match-winning 80 not out, putting on 121 with Niroshan Dickwella (80) in the home team’s total of 391-6.

Two hundreds from Andrew Strauss put England on top, but Virender Sehwag made a quickfire 83 before batting great Sachin Tendulkar (103 not out) and Yuvraj Singh (85 not out) took India to a four-wicket win.

Joe Root and Jonny Bairstow hit hundreds as England romped home by seven wickets in a series finale postponed from 2021 because of coronavirus concerns within the India camp.

Pakistan were in dire straits at 13-2 early in their chase but hundreds from Shan Masood and Younis Khan turned the tide before Misbah-ul-Haq’s match-winning 59 saw them to 382-3.

India made 471 after being sent in to bat by England captain Ben Stokes but the hosts were only six runs adrift on first innings. England then dismissed India for 364 and opener Ben Duckett’s superb 149 the cornerstone of a chase completed by Root and Jamie Smith. This was only the third Test with more than 350 runs in all four innings, after Ashes clashes at Adelaide in 1921 and Headingley in 1948.


Barrick, Komatsu sign $440 million equipment deal for Pakistan’s Reko Diq copper-gold mine

Updated 9 min 9 sec ago
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Barrick, Komatsu sign $440 million equipment deal for Pakistan’s Reko Diq copper-gold mine

  • Japanese firm to set up local mining company for long-term technical support at site
  • Deal includes ultra-class haul trucks, excavators and loaders built in US and Europe

ISLAMABAD: Barrick Gold Corporation and Japan’s Komatsu have finalized a $440 million agreement to supply mining equipment to Pakistan’s Reko Diq copper-gold project, with Komatsu also announcing plans to establish a local subsidiary to support operations, the company said on Wednesday.

Reko Diq is one of the world’s largest undeveloped copper and gold deposits, located in Pakistan’s mineral-rich Balochistan province near the volatile border with Iran and Afghanistan. The site is expected to play a key role in boosting Pakistan’s exports, attracting foreign investment, and supporting the country’s long-term energy and industrial needs through its vast copper reserves, which are critical for the global energy transition.

Reko Diq is jointly owned by Barrick (50 percent), Pakistan’s federal government (25 percent), and the Balochistan provincial government (25 percent). Construction is scheduled to begin in 2025, with first production targeted for 2028.

“The Reko Diq project represents a long-term investment in our future and that of mining in Pakistan, and our partnership with Komatsu is an important part of that vision,” Mark Bristow, President and CEO of Barrick, was quoted as saying in the Komatsu statement. 

“Komatsu equipment has proven its performance and reliability at our operations worldwide.”

Komatsu said the five-year deal marked its first major equipment placement in Pakistan and a deepening partnership with Barrick.

To support the deployment, Komatsu will establish Komatsu Pakistan Mining (SMC-Private) Limited, a dedicated entity for technical services and equipment support at Reko Diq. The firm also plans additional investment in its regional headquarters in Dubai to manage an expanded footprint in the region.

The deal includes the delivery of ultra-class mining equipment manufactured in the United States and Europe, including Komatsu 980E-5 haul trucks from Illinois, P&H electric rope shovels from Wisconsin, PC7000-11 excavators from Germany, and WE2350-2 electric wheel loaders from Texas.

“The scale and complexity of this project demands proven, high-performance equipment,” said Peter Salditt, President of Komatsu’s Mining Business Division.

“We are confident our ultra-class haul trucks, electric rope shovels, and other mining machines will meet the challenge.”

Komatsu said the partnership builds on previous equipment deployments at Barrick’s Lumwana mine in Zambia and its Nevada Gold Mines joint venture in the United States. The two companies signed a global framework agreement in October 2023 to strengthen cooperation across multiple sites.


Pakistani deputy PM discusses new investments in energy, infrastructure with Abu Dhabi Fund chief

Updated 42 min 8 sec ago
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Pakistani deputy PM discusses new investments in energy, infrastructure with Abu Dhabi Fund chief

  • Dar presents Al Suwaidi with Hilal-e-Quaid-e-Azam, one of Pakistan’s highest civil awards
  • UAE is Pakistan’s third largest trading partner after China and US, key source of remittances

ISLAMABAD: Pakistan Deputy Prime Minister and Foreign Minister Ishaq Dar met Director General of the Abu Dhabi Fund for Development (ADFD) Mohammed Saif Al-Suwaidi on Tuesday to discuss boosting development cooperation and new investments in energy and infrastructure, state-run Radio Pakistan reported.

The UAE is Pakistan’s third largest trading partner after China and the United States. More than 1.5 million Pakistanis live and work in the UAE, sending back billions of dollars in remittances annually. Bilateral trade between the two nations reached approximately $10.9 billion in fiscal year 2023–24, including $2.08 billion in exports and $6.33 billion in imports, according to Pakistani figures.

“They discussed enhancing development cooperation, expanding ADFD’s support for key infrastructure and energy projects in Pakistan, and exploring new avenues for sustainable investment,” Radio Pakistan said in a statement after Dar’s meeting with Al-Suwaidi. 

According to the report, both sides reaffirmed their commitment to “deepening economic ties and promoting shared growth and prosperity.”

Dar also presented Al Suwaidi with the Hilal-e-Quaid-e-Azam, one of Pakistan’s highest civil awards, on behalf of President Asif Ali Zardari, in recognition of his “exceptional contributions to the promotion of Pakistan-UAE cooperation,” the broadcaster said.

The ADFD has funded major development projects in Pakistan for decades, including roads, airports and energy infrastructure to support economic growth.

Last year, the UAE said it had committed $10 billion to invest in promising economic sectors in Pakistan.

Islamabad has been pushing for foreign investment in a bid to shore up its $350 billion economy, which has struggled with high inflation and low growth as it navigates tough reforms mandated by the International Monetary Fund.


Children in Pakistan among millions under threat as vaccine coverage faltering — study

Updated 25 June 2025
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Children in Pakistan among millions under threat as vaccine coverage faltering — study

  • Cases of polio, long eradicated in many areas thanks to vaccination, have been rising in Pakistan and Afghanistan
  • Researchers say setbacks threaten WHO goal of essential vaccines for 90 percent world’s children, adolescents by 2030

PARIS: Efforts to vaccinate children against deadly diseases are faltering across the world due to economic inequality, Covid-era disruptions and misinformation, putting millions of lives at risk, research warned Wednesday.

These trends all increase the threat of future outbreaks of preventable diseases, the researchers said, while sweeping foreign aid cuts threaten previous progress in vaccinating the world’s children.

A new study published in The Lancet journal looked at childhood vaccination rates across 204 countries and territories.

It was not all bad news.

An immunization program by the World Health Organization was estimated to have saved an estimated 154 million lives over the last 50 years.

And vaccination coverage against diseases such as diphtheria, tetanus, whooping cough, measles, polio and tuberculosis doubled between 1980 and 2023, the international team of researchers found.

However the gains slowed in the 2010s, when measles vaccinations decreased in around half of the countries, with the largest drop in Latin America.

Meanwhile in more than half of all high-income countries there were declines in coverage for at least one vaccine dose.

Then the Covid-19 pandemic struck.

Routine vaccination services were hugely disrupted during lockdowns and other measures, resulting in nearly 13 million extra children who never received any vaccine dose between 2020 to 2023, the study said.

This disparity endured, particularly in poorer countries. In 2023, more than half of the world’s 15.7 million completely unvaccinated children lived in just eight countries, the majority in sub-Saharan Africa, according to the study.

In the European Union, 10 times more measles cases were recorded last year compared to 2023.

In the United States, a measles outbreak surged past 1,000 cases across 30 states last month, which is already more than were recorded in all of 2024.

Cases of polio, long eradicated in many areas thanks to vaccination, have been rising in Pakistan and Afghanistan, while Papua New Guinea is currently enduring a polio outbreak.

“Routine childhood vaccinations are among the most powerful and cost-effective public health interventions available,” said senior study author Jonathan Mosser of the US-based Institute for Health Metrics and Evaluation (IHME).

“But persistent global inequalities, challenges from the COVID pandemic, and the growth of vaccine misinformation and hesitancy have all contributed to faltering immunization progress,” he said in a statement.

In addition, there are “rising numbers of displaced people and growing disparities due to armed conflict, political volatility, economic uncertainty, climate crises,” added lead study author Emily Haeuser, also from the IHME.

The researchers warned the setbacks could threaten the WHO’s goal of having 90 percent of the world’s children and adolescents receive essential vaccines by 2030.

The WHO also aims to halve the number of children who have received no vaccine doses by 2030 compared to 2019 levels.

Just 18 countries have achieved this so far, according to the study, which was funded by the Gates Foundation and the Gavi vaccine alliance.

The global health community has also been reeling since President Donald Trump’s administration drastically slashed US international aid earlier this year.

“For the first time in decades, the number of kids dying around the world will likely go up this year instead of down because of massive cuts to foreign aid,” Bill Gates said in a separate statement on Tuesday.

“That is a tragedy,” the Microsoft co-founder said, committing $1.6 billion to Gavi, which is holding a fund-raising summit in Brussels on Wednesday.


Pakistan says Trump still deserves Nobel for halting India clash, Iran-Israel fighting

Updated 25 June 2025
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Pakistan says Trump still deserves Nobel for halting India clash, Iran-Israel fighting

  • Islamabad says US president helped end conflicts with India and between Iran and Israel
  • Defense minister urges Trump to now work on implementing two-state solution for Palestine

ISLAMABAD: Pakistan’s Defense Minister Khawaja Asif on Tuesday defended Islamabad’s decision to recommend United States President Donald Trump for the 2026 Nobel Peace Prize, citing his role in brokering two ceasefires in under two months.

The government last week announced it would formally nominate Trump for what it called his “decisive diplomatic intervention” during last month’s military standoff with India, a brief but intense escalation in which the nuclear-armed rivals exchanged missile, drone and artillery strikes before the US brokered a truce on May 10.

The standoff, which killed nearly 70 people on both sides, renewed fears of a wider conflict between Pakistan and India, who have fought three full-scale wars, mostly over the disputed Himalayan region of Kashmir. Indian officials have denied that Trump played any role in securing the May 10 ceasefire, but Pakistan insists his behind-the-scenes push was key to defusing the crisis.

The nomination, however, has sparked public criticism after Trump last week launched strikes on Iranian nuclear facilities in retaliation for attacks on Israeli targets. The region narrowly avoided further escalation when Washington subsequently said it had brokered a ceasefire between Iran and Israel on Monday, ending nearly two weeks of missile and drone attacks that killed over 200 Iranians and about 30 Israelis.

“I believe that within just a month and a half, President Trump has managed two ceasefires,” Asif told Independent Urdu in an interview. “So, our endorsement for his Nobel Prize, it’s not just about one but two ceasefires that has further strengthened our case for it.”

Asif also credited Trump for preventing a wider regional war in the Middle East and urged him to build on the momentum by reviving efforts for a two-state solution in Palestine.

“And I would take it a step further that President Trump should now work toward a two-state solution and the establishment of a Palestinian state,” he said.

While reports of violations continued to emerge after the Iran-Israel ceasefire was announced, the truce has largely held under heavy US pressure. Trump, who campaigned on pledges to act as a “peacemaker” and quickly resolve conflicts in Ukraine and Gaza — both still ongoing five months into his presidency — has called the Iran-Israel truce a personal diplomatic triumph.

Trump has also claimed credit for mediating a deal between the Democratic Republic of Congo and Rwanda to defuse tensions over rebel groups operating near their border. He has also previously offered to mediate the decades-old Kashmir dispute between India and Pakistan and has sought to portray himself as a mediator in the long-running Serbia-Kosovo conflict.