UK authorizes Pfizer coronavirus vaccine for emergency use

Britain on Wednesday said it had approved the Pfizer-BioNTech vaccine for use across the country. (File/AFP)
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Updated 02 December 2020
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UK authorizes Pfizer coronavirus vaccine for emergency use

  • The vaccine remains experimental while final testing is done
  • Hancock said Britain expects to begin receiving the first shipment of 800,000 doses “within days,'' and people will begin receiving shots as soon as the NHS gets the vaccine

LONDON: British officials authorized a COVID-19 vaccine for emergency use on Wednesday, greenlighting the world’s first shot against the virus that’s backed by rigorous science and taking a major step toward eventually ending the pandemic.
The go-ahead for the vaccine developed by American drugmaker Pfizer and Germany's BioNTech comes as the virus surges again in the United States and Europe, putting pressure on hospitals and morgues in some places and forcing new rounds of restrictions that have devastated economies.
The Medicines and Healthcare Products Regulatory Agency, which licenses drugs in the UK, recommended the vaccine could be used after it reviewed the results of clinical trials that showed the vaccine was 95% effective overall — and that it also offered significant protection for older people, among those most at risk of dying from the disease. But the vaccine remains experimental while final testing is done.
“Help is on its way,'' British Health Secretary Matt Hancock told the BBC, adding that the situation would start to improve in the spring.
“We now have a vaccine. We're the first country in the world to have one formally clinically authorized but, between now and then, we've got to hold on, we've got to hold our resolve," he said.
Other countries aren’t far behind: Regulators in the United States and the European Union also are vetting the Pfizer shot along with a similar vaccine made by competitor Moderna Inc. British regulators also are considering another shot made by AstraZeneca and Oxford University.
Hancock said Britain expects to begin receiving the first shipment of 800,000 doses “within days,'' and people will begin receiving shots as soon as the National Health Service gets the vaccine.
Doses everywhere are scarce, and initial supplies will be rationed until more is manufactured in the first several months of next year.
A government committee will release details of vaccination priorities later Wednesday, but Hancock said nursing home residents, people over 80, and healthcare workers and other care workers will be the first to receive the shot.
Pfizer said it would immediately begin shipping limited supplies to the UK — and has been gearing up for even wider distribution if given a similar nod by the U.S. Food and Drug Administration, a decision expected as early as next week.
Pfizer CEO Albert Bourla called the UK decision “a historic moment.”
“We are focusing on moving with the same level of urgency to safely supply a high-quality vaccine around the world,” Bourla said in a statement.
While the UK has ordered 40 million doses of the Pfizer vaccine, enough for 20 million people, it’s not clear how many will arrive by year’s end. Hancock said the UK expects to receive “millions of doses" by the end of this year, adding that the actual number will depend on how fast Pfizer can produce the vaccine.
One concern about the Pfizer-BioNTech vaccine is that it must be stored and shipped at ultra-cold temperatures of around minus 70 degrees Celsius (minus 94 degrees Fahrenheit), adding to the challenge of distributing the vaccine around the world.
Pfizer says it has developed shipping containers that use dry ice to keep the vaccine cool. GPS-enabled sensors will allow the company to track each shipment and ensure they stay cold, the company says.
“Pfizer has vast experience and expertise in cold-chain shipping and has an established infrastructure to supply the vaccine worldwide, including distribution hubs that can store vaccine doses for up to six months," the company said in a statement.
The company also says it has agreed to work with other vaccine makers to ensure there is sufficient supply and a range of vaccines, “including those suitable for global access.”
Every country has different rules for determining when an experimental vaccine is safe and effective enough to use. Intense political pressure to be the first to roll out a rigorously scientifically tested shot colored the race in the US and Britain, even as researchers pledged to cut no corners. In contrast, China and Russia have offered different vaccinations to their citizens ahead of late-stage testing.
The shots made by US-based Pfizer and its German partner BioNTech were tested in tens of thousands of people. And while that study isn’t complete, early results suggest the vaccine is 95% effective at preventing mild to severe COVID-19 disease. The companies told regulators that of the first 170 infections detected in study volunteers, only eight were among people who’d received the actual vaccine and the rest had gotten a dummy shot.
“This is an extraordinarily strong protection,” Dr. Ugur Sahin, BioNTech’s CEO, recently told The Associated Press.
The companies also reported no serious side effects, although vaccine recipients may experience temporary pain and flu-like reactions immediately after injections.
Final testing must still be completed. Still to be determined is whether the Pfizer-BioNTech shots protect against people spreading the coronavirus without showing symptoms. Another question is how long protection lasts.
The vaccine also has been tested in only a small number of children, none younger than 12, and there’s no information on its effects in pregnant women.


India’s leader Modi touted all was well in Kashmir. A massacre of tourists shattered that claim

Updated 13 sec ago
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India’s leader Modi touted all was well in Kashmir. A massacre of tourists shattered that claim

  • The attack outraged people in Kashmir and India, where it led to calls of swift action against Pakistan

SRINAGAR, India: Hundreds of Indian tourists, families and honeymooners, drawn by the breathtaking Himalayan beauty, were enjoying a picture-perfect meadow in Kashmir. They didn’t know gunmen in army fatigues were lurking in the woods.
When the attackers got their chance, they shot mostly Indian Hindu men, many of them at close-range, leaving behind bodies strewn across the Baisaran meadow and survivors screaming for help.
The gunmen quickly vanished into thick forests. By the time Indian authorities arrived, 26 people were dead and 17 others were wounded.
India has described the April 22 massacre as a terror attack and blamed Pakistan for backing it, an accusation denied by Islamabad. India swiftly announced diplomatic actions against its archrival Pakistan, which responded with its own tit-for-tat measures.
The assailants are still on the run, as calls in India for military action against Pakistan are growing.
World leaders have been scrambling to de-escalate the tensions between two nuclear-armed neighbors, which have historically relied on third countries for conflict management.
But the massacre has also touched a raw nerve.
Early on Wednesday, India fired missiles that struck at least three locations inside Pakistani-controlled territory, according to Pakistani security officials who spoke on condition of anonymity because they were not authorized to talk to the media. India said it was striking infrastructure used by militants.
India admits security lapse
Indian Prime Minister Narendra Modi’s administration has governed Kashmir with an iron fist in recent years, claiming militancy in the region was in check and a tourism influx was a sign of normalcy returning.
Those claims now lie shattered.
Security experts and former intelligence and senior military officers who have served in the region say Modi’s government — riding on a nationalistic fervor over Kashmir to please its supporters — missed warning signs.
The government acknowledged that in a rare admission.
Two days after the attack, Kiren Rijiju, India’s parliamentary affairs minister, said that a crucial all-party meeting discussed “where the lapses occurred.”
“We totally missed ... the intentions of our hostile neighbor,” said Avinash Mohananey, a former Indian intelligence officer who has operated in Kashmir and Pakistan.
The meadow, near the resort town of Pahalgam, can be reached by trekking or pony rides, and visitors cross at least three security camps and a police station to reach there. According to Indian media, there was no security presence for more than 1,000 tourists that day.
Pahalgam serves as a base for an annual Hindu pilgrimage that draws hundreds of thousands of people from across India. The area is ringed by thick woods that connect with forest ranges in the Jammu area, where Indian troops have faced attacks by rebels in recent years after fighting ebbed in the Kashmir Valley, the heart of an anti-India rebellion.
The massacre brought Modi’s administration almost back to where it started when a suicide car bombing in the region in 2019 prompted his government to strip Kashmir of its semi-autonomy and bring it under direct federal rule. Tensions have simmered ever since, but the region has also drawn millions of visitors amid a strange calm enforced by an intensified security crackdown.
“We probably started buying our own narrative that things were normal in Kashmir,” Mohananey said.
In the past, insurgents have carried out brazen attacks and targeted Hindu pilgrims, Indian Hindu as well as Muslim immigrant workers, and local Hindus and Sikhs. However, this time a large number of tourists were attacked, making it one of the worst massacres involving civilians in recent years.
The attack outraged people in Kashmir and India, where it led to calls of swift action against Pakistan.
Indian television news channels amplified these demands and panelists argued that India should invade Pakistan. Modi and his senior ministers vowed to hunt down the attackers and their backers.
Experts say much of the public pressure on the Indian government to act militarily against Pakistan falls within the pattern of long, simmering animosity between both countries.
“All the talk of military options against Pakistan mainly happens in echo chambers and feeds a nationalist narrative,” in India, New Delhi-based counterterrorism expert Ajai Sahni said.
“It doesn’t matter what will be done. We will be told it was done and was a success,” he said. “And it will be celebrated nonetheless.”
Modi’s optimism misplaced, experts say
Experts also say that the Modi government’s optimism was also largely misplaced and that its continuous boasting of rising tourism in the region was a fragile barometer of normalcy. Last year, Omar Abdullah, Kashmir’s top elected official, cautioned against such optimism.
“By this attack, Pakistan wants to convey that there is no normalcy in Kashmir and that tourism is no indicator for it. They want to internationalize the issue,” said D.S. Hooda, former military commander for northern India between 2014 to 2016.
Hooda said the “choice of targets and the manner in which the attack was carried out indicates that it was well-planned.”
“If there would have been a good security cover, maybe this incident would not have happened,” he said.
India sees Pakistan connection to the attack
Indian security experts believe the attack could be a retaliation for a passenger train hijacking in Pakistan in March by Baloch insurgents. Islamabad accused New Delhi of orchestrating the attack in which 25 people were killed. India denies it.
Mohananey said that Indian authorities should have taken the accusations seriously and beefed-up security in Kashmir, while arguing there was a striking similarity in both attacks since only men were targeted.
“It was unusual that women and children were spared” in both cases, Mohananey said.
Two senior police officers, who have years of counterinsurgency experience in Kashmir, said after the train attack in Pakistan that they were anticipating some kind of reaction in the region by militants.
The officers, who spoke on condition of anonymity because of the sensitivity of the matter, said that security officials perceived the threat of an imminent attack, and Modi’s inauguration of a strategic rail line in the region was canceled. A large-scale attack on tourists, however, wasn’t anticipated, because there was no such precedence, the officers said.
Hooda, who commanded what New Delhi called “surgical strikes” against militants in the Pakistan-controlled part of Kashmir in 2016, said that the attack has deepened thinking that it was time to tackle the Pakistani state, not just militants.
Such calculus could be a marked shift. In 2016 and 2019, India said that its army struck militant infrastructure inside Pakistan after two major militant attacks against its soldiers.
“After this attack,” Hooda said, India wants to stop Pakistan “from using terrorism as an instrument of state policy.”
“We need to tighten our security and plug lapses, but the fountainhead of terrorism needs to be tackled,” Hooda said. “The fountainhead is Pakistan.”


Trump says only 21 hostages held by Hamas in Gaza now believed to be alive

Updated 23 min 12 sec ago
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Trump says only 21 hostages held by Hamas in Gaza now believed to be alive

WASHINGTON: President Donald Trump said Tuesday that three hostages held by Hamas in Gaza have died, leaving only 21 believed to be still living.
“As of today, it’s 21, three have died,” Trump said of the hostages being held by Hamas, noting until recently it had been 24 people believed to be living. He did not elaborate on the identities of those now believed to be dead, nor how he had come to learn of their deaths. “There’s 21, plus a lot of dead bodies,” Trump said.
One American, Edan Alexander, had been among the 24 hostages believed to be alive, with the bodies of several other Americans also held by Hamas after its Oct. 7, 2023 assault on Israel.
The president’s comments came as Israel approved plans on Monday to seize the Gaza Strip and to stay in the Palestinian territory for an unspecified amount of time, in a bid to recover the hostages and try to fulfill its war aims of destroying Hamas. If implemented, the move would vastly expand Israel’s operations there and likely draw fierce international opposition.


Columbia University lays off nearly 180 after Trump pulled $400M over his antisemitism concerns

Updated 42 min 39 sec ago
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Columbia University lays off nearly 180 after Trump pulled $400M over his antisemitism concerns

  • Pro-Palestinian demonstrators set up an encampment and seized a campus building in April, leading to dozens of arrests and inspiring a wave of similar protests nationally

NEW YORK: Columbia University said Tuesday that it will be laying off nearly 180 staffers in response to President Donald Trump’s decision to cancel $400 million in funding over the Manhattan college’s handling of student protests against the war in Gaza.
Those receiving non-renewal or termination notices Tuesday represent about 20 percent of the employees funded in some manner by the terminated federal grants, the university said in a statement Tuesday.
“We have had to make deliberate, considered decisions about the allocation of our financial resources,” the university said. “Those decisions also impact our greatest resource, our people. We understand this news will be hard.”
Officials are working with the Trump administration in the hopes of getting the funding restored, they said, but the university will still pull back spending because of uncertainty and strain on its budget.
Officials said the university will be scaling back research, with some departments winding down activities and others maintaining some level of research while pursuing alternate funding.
In March, the Trump administration pulled the funding over what it described as the Ivy League school’s failure to squelch antisemitism on campus during the Israel-Hamas war that began in October 2023.
Within weeks, Columbia capitulated to a series of demands laid out by the Republican administration as a starting point for restoring the funding.
Among the requirements was overhauling the university’s student disciplinary process, banning campus protesters from wearing masks, barring demonstrations from academic buildings, adopting a new definition of antisemitism and putting the Middle Eastern studies program under the supervision of a vice provost who would have a say over curriculum and hiring.
After Columbia announced the changes, US Education Secretary Linda McMahon said the university was ” on the right track,” but declined to say when or if Columbia’s funding would be restored. Spokespersons for the federal education department didn’t immediately respond to an email seeking comment Tuesday.
Columbia was at the forefront of US campus protests over the war last spring. Pro-Palestinian demonstrators set up an encampment and seized a campus building in April, leading to dozens of arrests and inspiring a wave of similar protests nationally.
Trump, when he retook the White House in January, moved swiftly to cut federal money to colleges and universities he viewed as too tolerant of antisemitism.


Trump hopes India-Pakistan clashes end ‘very quickly’

Updated 47 min 27 sec ago
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Trump hopes India-Pakistan clashes end ‘very quickly’

WASHINGTON: US President Donald Trump said Tuesday he hoped clashes between nuclear-armed India and Pakistan end “very quickly,” after New Delhi’s forces launched strikes and Islamabad vowed retaliation.
“It’s a shame, we just heard about it,” Trump said at the White House, after the Indian government said it had hit “terrorist camps” on its western neighbor’s territory following a deadly attack on tourists in Indian-administered Kashmir.
“I guess people knew something was going to happen based on the past. They’ve been fighting for many, many decades and centuries, actually, if you really think about it,” he added.
India and Pakistan have fought three full-scale wars since gaining independence from the British in 1947. Both claim Kashmir in full but administer separate portions of the disputed region.
“I just hope it ends very quickly,” said Trump.
India had been widely expected to respond militarily since gunmen shot dead 26 people in Indian-administered Kashmir, mostly Hindus.
New Delhi has blamed militants that it has said were from Pakistan-based group Lashkar-e-Taiba, a UN-designated terrorist organization.
Pakistan’s army said the Indian strikes targeted three sites in Pakistan-administered Kashmir and two in Punjab province, the country’s most populous.
Islamabad said that three civilians, including a child, had been killed in Indian strikes.
The Indian strikes came just hours after the US State Department issued a fresh call for calm.
“We continue to urge Pakistan and India to work toward a responsible resolution that maintains long-term peace and regional stability in South Asia,” State Department spokeswoman Tammy Bruce told reporters.
Her statement came after Indian Prime Minister Narendra Modi warned of stopping water from flowing across borders following the Kashmir attack.


‘World cannot afford’ India-Pakistan confrontation: UN

Updated 54 min 46 sec ago
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‘World cannot afford’ India-Pakistan confrontation: UN

UNITED NATIONS: UN Secretary-General Antonio Guterres was “very concerned” about Indian military strikes on Pakistan, his spokesperson said on Tuesday, hours after India said it hit nine sites in Pakistani territory.
“The Secretary-General is very concerned about the Indian military operations across the Line of Control and international border. He calls for maximum military restraint from both countries. The world cannot afford a military confrontation between India and Pakistan,” said Stephane Dujarric, the spokesperson.